Ikhithi Yokuhlola ye-Allergen-specific IgE
| Isixazululo se-Chemiluminescent (Ukungezwani komzimba) | ||
| Uchungechunge | Igama Lomkhiqizo | Igama Lomkhiqizo |
| I-Allergen-specific IgE | Uthuli lwendlu D1 | I-Ribwort W9 |
| Izimbuzane zothuli D2 | I-Kentucky blue grass G8 | |
| I-Cat dander E1 | I-rye etshaliwe G12 | |
| I-dog dander E5 | I-Pistachio F203 | |
| Imbewu yeSesame F10 | I-maple leaf sycamore, indiza yaseLondon, i-Plane tree T11 | |
| I-Peanut F13 | I-Latex K82 | |
| Ubhontshisi wesoya F14 | I-Olive T9 | |
| Ubisi F2 | I-Strawberry F44 | |
| Inkalankala F23 | I-Cypress T23 | |
| I-shrimp F24 | I-Almond F20 | |
| Iqanda F245 | Izinqumo ze-carbohydrate eziphambanayo ze-CCD | |
| Inyama yenkomo F27 | Umlotha Omhlophe T15 | |
| I-Codfish F3 | I-Apple F49 | |
| Ukolweni F4 | I-Cladosporium herbarum M2 | |
| Inyama yemvu F88 | I-Penicilloyl G C1 | |
| Uthuli lwasendlini H1 | I-Penicilloyl V C2 | |
| Iphela, isiJalimane I6 | I-Amoxicillin C6 | |
| I-Aspergillus fumigatus M3 | I-Guinea yengulube epithelium E6 | |
| I-Alternaria M6 | I-Rye F5 | |
| I-Willow T12 | Ilayisi F9 | |
| I-ragweed evamile W1 | Utamatisi F25 | |
| Mugwort W6 | Ingulube F26 | |
| I-Cocksfoot G3 | Isanqante F31 | |
| I-birch yesiliva evamile T3 | Amazambane F35 | |
| I-Hazel T4 | Imvubelo F45 | |
| Iqanda elimhlophe F1 | Isikhuphasha seqanda F75 | |
| Timothy utshani G6 | I-Gluten F79 | |
| I-Garlic F47 | Ipentshisi F95 | |
| I-Kiwi F84 | Ibhilikosi F237 | |
| Isilimo esidliwayo esinamagatsha anamanzi F85 | I-Walnut F256 | |
| I-mustard F89 | Utshani be-Bermuda G2 | |
| Ubhanana F92 | Johnson utshani G10 | |
| Oak T7 | Utshani bevelvet G13 | |
| I-Goosefoot W10 | I-Bahia grass G17 | |
| I-Hazel nut F17 | Isihlungu sezinyosi zoju I1 | |
| I-Horse dander E3 | Ubuthi bejakhethi ephuzi I3 | |
| I-Rabbit epithelium E82 | Isihlungu somuvi wephepha I4 | |
| I-Hamster epithelium E84 | I-Penicillium chrysogenum M1 | |
| I-Meadow fescue G4 | I-grey alder T2 | |
| I-Rye-grass G5 | I-Mountain juniper T6 | |
| Ukolo olinyiwe G15 | I-Eastern Wall pellitory W19 | |
| Ibhishi T5 | Ukusabalalisa i-pellitory W21 | |
| Umlotha waseYurophu T25 | I-Japan Hop W22 | |
| I-Dandelion W8 | / | |
Izifo ezingezwani nomzimba yizimo lapho isiguli sihogela khona noma sidle izinto eziqukethe izakhi ezingezwani nomzimba (okuthiwa izinto ezingezwani nomzimba noma izinto ezingezwani nomzimba, izinto ezingezwani nomzimba) ezibangela amaseli B omzimba ukuthi akhiqize i-immunoglobulin E (IgE) eyeqile.Lapho amasosha omzimba e-IgE evezwa kabusha ezintweni ezingezwani ne-vivo, axhumanisa nezinto ezingezwani nomzimba futhi abophe i-FcεRI ephezulu ye-affinity receptor ebusweni bama-mast cells nama-basophil, okuholela ekuqongeleleni kwe-FcεRI kanye nokusebenza kwe-mast cell kanye ne-basophil.Ngesikhathi sokusebenza, amangqamuzana e-mast adiliza futhi akhulule i-histamine, umlamuleli ovuthayo ogcinwe kuma-cytoplasmic granules, kanye ne-leukotrienes, i-immunoreactive prostaglandin, ama-cytokines nama-chemokines anjenge-IL-4 ne-IL-5 ahlanganiswe ngendlela ye-arachidonic acid, eqala izimpawu zesifo sokungezwani komzimba ( ukungezwani komzimba nezinye izifo), njengesifuba somoya esingezwani nomzimba, i-hay fever, i-urticaria, i-rhinitis engezwani ne-eczema, i-allergic dermatitis, i-conjunctivitis kanye nokungasebenzi kahle kwe-gastrointestinal.Ukutholwa kwezinhlobo ezahlukene zezivikeli mzimba ze-IgE eziqondene ne-allergen ku-serum kungasetshenziswa ukuze kuhlonzwe ukuthi ingabe ezinye izimpawu zidalwa ukungezwani komzimba emsebenzini womtholampilo.
I-Immunoglobulin IgE iyi-antibody elamula ukungezwani komzimba nohlobo I, futhi i-IgE eqondene ne-allergen ikhona ku-serum yeziguli ezingezwani nazo, ebizwa ngokuthi i-IgE ethile.Labo abangezwani nobisi bane-IgE ngokumelene nezinto ezingezwani nobisi;labo abangezwani nempova ye-artemisinin bane-IgE ngokumelene nempova.Ama-Allergens angena emzimbeni ukuze enze ukukhiqizwa kwe-IgE ethile, ebophezela kuma-mast cell kanye nama-basophil, okuvumela umzimba ukuthi ungene esimweni sokuzwela okuthile kulokhu kungezwani komzimba.Lapho i-allergen iphinda ithintana futhi, ibophezela ku-IgE receptor kulwelwesi lweseli futhi ibangele uchungechunge lokusabela kwamakhemikhali e-biochemical, kamuva okukhulula abaxhumanisi be-bioactive abahlukahlukene abahlobene nokungezwani komzimba nokuvuvukala, njenge-histamine.Njengoba leli qembu lamasosha omzimba likwazi ukubophezela kuphela kule allergen, kuyadingeka ukusebenzisa i-allergen ehlanzekile esikhundleni se-anti-IgE ukuze ibonwe.Kunezindlela eziningi eziqondile zokuhlola ze-IgE, njenge-ELISA, FEIA, kanye ne-immunoblotting ezivame ukusetshenziswa emisebenzini yomtholampilo.
