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imikhiqizo

I-Cardiac Marker Chemiluminecense Immunoassay Kit

Cardiac Marker Chemiluminescense Immunoassay Kit Featured Image
  • Cardiac Marker Chemiluminescense Immunoassay Kit

incazelo emfushane:

Omaka benhliziyo basetshenziswa kakhulu ukuxilonga ukulimala kweseli le-myocardial.I-cTnI ne-cTnT zidlala indima enkulu ekulawuleni ukufinyela kwemisipha yenhliziyo futhi ziyizimpawu eziqondile nezibucayi zokulimala kwe-myocardial.I-phospholipase A2 ehlotshaniswa ne-Lipoprotein (LP-PLA2) iwuphawu oluqondile lwemithambo lokuvuvukala.Uhlobo lwe-Cardiac fatty binding protein (H-FABP) iyiphrotheni ethwala i-fatty acid eyinhloko, ewuphawu oluthembisayo kakhulu lokulimala kwe-myocardial.


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Isixazululo se-Clinical Chemistry

Uchungechunge

Igama Lomkhiqizo

Abbr

Izimpawu Zenhliziyo

I-L-Lactate Dehydrogenase

I-LDH

I-α-Hydroxybutyrate Dehydrogenase

α-HBDH

I-Creatine Kinase

CK

I-Creatine Kinase Isoenzyme-MB

CK-MB

I-Lactate Dehydrogenase isoenzyme-1

I-LDH1

I-Heart Fatty Binding Amaprotheni

H-FABP

I-Myocardial enzyme spectrum iwuhlobo olulodwa lokuhlolwa kwamakhemikhali egazi, okuvame ukusetshenziswa ekuxilongweni komtholampilo kwe-myocarditis kanye ne-acute myocardial infarction.Izinkomba ezihlobene nephrofayili ye-enzyme ye-myocardial zihlanganisa i-lactate dehydrogenase, i-α -hydroxybutyrate dehydrogenase, i-creatine kinase, i-creatine kinase isoenzyme MB, i-lactate dehydrogenase isoenzyme 1. Ngaphezu kwalokho, amaprotheni e-cardiac fatty binding amaprotheni nawo ahlobene nemisipha yenhliziyo.

I-Lactate dehydrogenase iyi-enzyme ye-cytoplasmic esatshalaliswa kabanzi ezicutshini ezihlukahlukene, ikakhulukazi enhliziyweni, isibindi, imisipha nezinso.I-LDH ku-serum ingahlukaniswa ngama-isoenzymes amahlanu ahlukene nge-electrophoresis.I-LDH ephakeme ijwayelekile ku-myocardial infarction, i-hepatitis kanye ne-pulmonary infarction.Njengamanje, kuvame ukusetshenziselwa ukuxilongwa komtholampilo kwe-myocardial infarction nesifo sesibindi.

Isilinganiso seSerum α-HBDH/LDH kwesinye isikhathi singasetshenziswa ukuhlukanisa isifo senhliziyo nesifo sesibindi.Isilinganiso siphezulu sesifo senhliziyo futhi siphansi kwesifo sesibindi.Ngaphezu kwalokho, i-serum HBDH iyanda ku-anemia ye-hemolytic.

I-Creatine kinase itholakala ikakhulukazi kumisipha yohlaka lwamathambo kanye ne-myocardium futhi ingenye yama-enzyme e-myocardial avame ukusetshenziswa emtholampilo.Ukuphakama kwayo kuvamile ku-acute myocardial infarction, i-myocarditis yegciwane, i-progressive muscular atrophy, ingozi ye-cerebrovascular, i-meningitis, iziguli zebanga eliphansi A.Ukucaciswa kwe-CK ekuxilongweni okusizayo kwe-myocardial infarction kwakuphakeme kune-AST ne-LDH.I-Creatine kinase iqukethe ama-subunit amabili uM no-B ukuze akhe ama-dimers amathathu - CK-BB, CK-MB, kanye ne-CK-MM.

I-CK-MB itholakala ikakhulukazi ku-myocardium, ngakho-ke ibonwa ngokomtholampilo njengenkomba ebalulekile yokuxilongwa kwe-myocardial infarction kanye nokunqunywa kwe-myocardial necrosis, futhi ingenye yezinkomba ezibalulekile zomtholampilo ze-enzyme ye-myocardial spectrum.

I-LDH1, i-LDH2, i-LDH3, i-LDH4 ne-LDH5 yizinhlobo eziningi ze-isozyme ze-lactate dehydrogenase ku-myocardium yomuntu, izinso neseli elibomvu legazi, i-LDH1 ne-LDH2 iyakhuphuka, kanti i-LDH1/LDH2>1 ibonakala ku-acute myocardial infarction, i-hemolytic anemia nezinye. izifo.

I-Cardiac fatty binding protein iwuhlobo olusha lwamaprotheni amancane e-cytoplasmic agcwele enhliziyweni.Iqondise kakhulu inhliziyo, kodwa iphinde ivezwe ekugxilweni okuphansi kwezicubu ngaphandle kwenhliziyo.I-HFABP ingase ibonakale egazini kusenesikhathi esingamahora angu-1 kuya kwangu-3 ngemva kokuqala kobuhlungu besifuba, ifinyelela phezulu emahoreni angu-6 kuya kwangu-8 futhi ibuyele emazingeni avamile e-plasma phakathi kwamahora angu-24 kuya kwangu-30 ngemva kokuqala kokulimala kwe-myocardial ischemic.I-Cardiac fatty acid ebopha iphrotheni ye-cytoplasmic yakhiwe ngama-amino acid angu-132 futhi inesisindo samangqamuzana angu-15 kDa.

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