Ikhithi Yokuhlola Umaka Wenhliziyo
| Isixazululo se-Chemiluminescent (Izinto Ezijwayelekile) | ||
| Uchungechunge | Igama Lomkhiqizo | Igama Lomkhiqizo |
| Umaka Wenhliziyo | Troponin I | cTnI |
| I-Creatine Kinase Isoenzyme-MB | CK-MB | |
| I-Myohemoglobin | Myo | |
| Isici Esikhuthaza Ukukhula 2 | ST2 | |
| I-Phospholipase A2 ehlotshaniswa ne-Lipoprotein | I-LP-PLA2 | |
| I-D-Dimer | I-D-Dimer | |
| Iphrotheni ebopha i-Fatty Acid ehlanganisa inhliziyo | H-FABP | |
| I-S100-β Amaprotheni | I-S100-β | |
| I-Brain Natriuretic Peptide | I-BNP | |
| I-N-Terminal pro-Brain Natriuretic Peptide | I-NT-proBNP | |
Omaka benhliziyo basetshenziswa kakhulu ukuxilonga ukulimala kweseli le-myocardial.
I-cTnI ne-cTnT zidlala indima enkulu ekulawuleni ukufinyela kwemisipha yenhliziyo futhi ziyizimpawu eziqondile nezibucayi zokulimala kwe-myocardial.I-myoglobin ikhona emisipheni ye-myocardial ne-skeletal, futhi idedelwa egazini lapho izicubu zamathambo kanye nokulimala kwe-myocardial (i-acute myocardial infarction (mi), ukunyakaza ngokweqile kanye nesifo semisipha, Ku-acute myocardial infarction, ukuhlushwa kwe-myoglobin ku-serum kuchezuka enanini elijwayelekile ngaphakathi kwe-2- Amahora angu-3 enkathi yokuqala yobuhlungu benhliziyo ngenxa yokuphazamiseka kwezicubu ze-myocardial, futhi yafinyelela inani eliphakeme kakhulu phakathi kwamahora angu-6-9, futhi yabuyiselwa kunani elivamile ngemva kwamahora angu-24. I-Ck-MB ingenye yama-isomer amathathu e-Creatine Kinase (CK) ), ezinye ezimbili ziyi-CK-BB kanye ne-CK-MM.Uhlobo lwe-MB lutholakala kakhulu kuma-cardiomyocytes, ngakho i-CK-MB inokucaciswa okuphezulu kwe-myocardium.Ku-Acute Myocardial Infarction (AMI), ikhishelwa egazini.Ck-MB inyuka emahoreni angama-4-6 ngemuva kokuqala kwe-myocardial infarction, ifinyelela isiqongo emahoreni angama-24, futhi ibuyele kokujwayelekile phakathi nezinsuku ezi-3.
I-phospholipase A2 ehlotshaniswa ne-Lipoprotein (LP-PLA2) iwuphawu oluqondile lwemithambo lokuvuvukala.Kutholwe ukuthi i-LP-PLA2 iyingozi ezimele yesifo senhliziyo kanye ne-ischemic stroke.Okusanda kugunyazwa yi-US FDA ukubikezela ingozi ye-coronary heart disease kanye ne-ischemic stroke, amazinga e-LP-PLA2 ahambisana ne-logarithmic ehambisana nesifo senhliziyo kanye nokufa kwemithambo.I-D-dimer iwumkhiqizo othile wokucekela phansi we-fibrin monomer ephambaniswe yi-activator XIII futhi i-hydrolyzed nge-enzyme ye-fibrinolytic, okuwumaka othize wenqubo ye-fibrinolytic.Ngesikhathi se-acute myocardial infarction, amazinga e-plasma e-DD akhuphuka kakhulu.Iphrotheni ye-S100 futhi ebizwa ngokuthi iphrotheni ethile yezinzwa emaphakathi njengezimpawu zamakhemikhali ezinto eziphilayo zokulimala kobuchopho ekulimaleni kobuchopho ngemva kwesikhathi esithile, kodwa futhi ihlobene eduze nedigri yokulimala kobuchopho kanye ne-prognosis kanye, ukuzinza okungcono, ukutholwa kwayo kokuminyana kusiza ukwahlulela komtholampilo kwezicubu zezinzwa. usayizi wesilonda, umphumela wokwelashwa kanye nokwahlulela ukubikezela, njll.
I-Cardiac type fatty binding protein (H-FABP) iyiphrotheni ephethe i-fatty acid.I-cardio-specific kakhulu (okungukuthi, evezwa ngokuyinhloko ezicutshini zenhliziyo), kodwa futhi ivezwa ekugxilweni okuphansi kwezicubu ngaphandle kwenhliziyo.Ngemva kokuqala kokulimala kwe-myocardial ischemic, i-H-FABP ingase ibonakale egazini kusenesikhathi esingamahora angu-1 kuya kwangu-3 ngemva kokuqala kobuhlungu besifuba, ifinyelela phezulu emahoreni angu-6 kuya kwangu-8 futhi ibuyele emazingeni avamile e-plasma phakathi kwamahora angu-24 kuya kwangu-30.Iwuphawu oluthembisayo kakhulu lokulimala kwe-myocardial, futhi izinga eliphezulu le-plasma H-FABP lingatholwa esigabeni sokuqala se-acute myocardial infarction (0-3 h), futhi ukukhululwa kwayo ngokuyinhloko kuncike ekulimaleni kwe-myocardial ischemia.I-PreproBNP ihlanganiswa ku-cardiomyocyte futhi iguqulwa ibe i-molecule eyandulela ebizwa ngokuthi i-proBNP.I-ProBNP ibe isiboliswa ibe yi-BNP esebenza ngokusebenza ngokomzimba, kanye nocezu lokucekela phansi i-NT-probNP.Imihlahlandlela ye-European Heart Society yokwehluleka kwenhliziyo incoma i-BNP ne-NT-proBNP njengezimpawu zamangqamuzana zokutholwa kokuxilonga kokuqala kokwehluleka kwenhliziyo.I-ST2 iyiphrotheni yenhliziyo ekhiqizwa ama-cardiomyocyte ngaphansi kokucindezeleka kwe-biomechanical.I-sST2 eyeqile ku-serum ingenza i-myocardium ingabi nokuvikelwa okwanele kwe-IL-33 phakathi nokulimala kokucindezeleka komshini, okuholela ekulungiseni kabusha kwe-myocardial kanye nokungasebenzi kahle kwenhliziyo.Ukwanda okuqhubekayo kwezinga le-ST2 kubonisa ukuqhubeka okuqhubekayo kwe-myocardial fibrosis nokulungiswa kabusha, kanye nokuqiniswa kwenqubo ye-pathological yokuhluleka kwenhliziyo.I-ST2 isetshenziselwa ukuhlolwa komtholampilo kweziguli ezine-HF eyingozi futhi engapheli, ukuze kuqondiswe ukwelashwa kwe-HF. Ukunqunywa kwe-ST2 kuhlanganiswe ne-BNP noma i-nT-probNP kungase kuthuthukise ukunemba kokuhlola ukuqagela kokuhluleka kwenhliziyo.
