Ikhithi Yokuhlola Isifo Samathumbu Esivuvukalayo(IBD).
| Isixazululo se-Chemiluminescent (i-Autoimmune Diseases) | ||
| Uchungechunge | Igama Lomkhiqizo | Abbr |
| Isifo samathumbu esivuvukalayo | I-Anti-Saccharomyces Cerevisiae IgG | I-ASCA-IgG |
| I-Anti-Saccharomyces Cerevisiae IgA | I-ASCA-IgA | |
| I-Anti-Intestinal Goblet Cell IgG | I-GAB IgG | |
| I-Anti-Intestinal Goblet Cell IgA | I-GAB IgA | |
| I-Elastase | I-Elastase | |
| Catherine G | CG | |
| I-Lactoferrin | LF | |
I-Inflammatory Bowel Disease (IBD) yisifo somtholampilo esingajwayelekile esine-etiology engaziwa.Kungokokuvuvukala kwamathumbu okungaqondile, okuhlanganisa nesifo sikaCrohn (CD) kanye ne-ulcerative colitis (UC).I-CD yatholwa nguBurrill Crohn ngo-1932 futhi iwukuphazamiseka kokuvuvukala kwamathumbu esizathu esingaziwa okungenzeka noma kuphi emgudwini wamathumbu, kodwa ngokuqagela kwe-ileum yokugcina kanye nekholoni yangakwesokudla.I-UC ivame kakhulu emazweni asentshonalanga.Ngokuthuthukiswa kwamazinga okuphila kazwelonke, izinga lokutholakala kwezifo zamathumbu ezivuthayo liye landa kakhulu eminyakeni yamuva.Ucwaningo lwakamuva lubike ukuthi i-ASCA iyi-serum antibody esebenzayo ku-Anti-Saccharomyces cerevisiae wall mannan, okuhlanganisa kokubili i-IgG ne-IgA.I-ASCA iwumaka we-serological weziguli eziningi ezine-CD futhi ucwaningo lwakamuva luthole ukuthi ukuba khona kwakho kokubili kwe-ASCA IgG kanye ne-ASCA IgA kunokucaciswa okungu-100% kwe-CD.Ngakho-ke, ukutholwa kwe-ASCA kungase kube wusizo ekuhlonzeni i-CD ne-UC kwezinye iziguli.
Ngokubandakanyeka kwezici zemvelo kanye nokubamba iqhaza kwezitshalo zamathumbu emathunjini, abantu abathintekayo baqala ukuphendula kwamasosha omzimba emathunjini, okuholela ekulimazeni kwe-intestinal mucosal barrier, i-hyperplasia yokuvuvukala nezinye izinguquko ze-pathological.I-IBD ihlanganisa i-ulcerative colitis (UC) nesifo sikaCrohn (CD).Cishe i-5% -15% yeziguli ze-IBD kunzima ukuzibona, okubizwa ngokuthi isifo sofuba esingahlanjululwa (IBDU) kanye ne-indeterminate colitis (IC).I-IBD ivame kakhulu emazweni asentshonalanga.Ngokuthuthuka kwamazinga okuphila kazwelonke, izinga lezigameko zezifo ezivuvukalayo zamathumbu eChina lenyuke kakhulu eminyakeni yamuva.I-anti-intestinal goblet epithelial cell antibody (GAB) okwamanje ithathwa njengamasosha omzimba athile e-serum ye-UC futhi alungele ukuhlolwa kusenesikhathi.Ama-titre aphezulu e-anti-intestinal goblet cell antibody atholakala kakhulu ku-ulcerative colitis nakwezinye iziguli ezine-CD.Futhi ezihlotsheni eziseduze zeziguli ezinesifo sofuba, ukubikezela ukuthambekela kokugula kwamathumbu okuvuvukala.Ukutholwa kwe-anti-intestinal goblet cell antibody ezihlotsheni eziseduze zeziguli ezine-IBD kubikezela ukubikezelwa kwe-IBD.
