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imikhiqizo

I-Lipid Metabolism Chemiluminecense Immunoassay Kit

Lipid Metabolism Chemiluminescense Immunoassay Kit Featured Image
  • Lipid Metabolism Chemiluminescense Immunoassay Kit

incazelo emfushane:

I-Lipid metabolism ibhekisa ekwakhiweni kwamafutha amaningi emzimbeni ngokufakwa kwenyongo ibe yizinhlayiyana ezincane, i-pancreatic kanye ne-endocrine lipase hydrolysis yama-fatty acids abe ama-fatty acids mahhala kanye ne-glycerol monoesters.Ukutholwa kwezinto ze-lipid kunenani eliphakeme kanye nokubaluleka kokuxilongwa okuyisizayo kanye nokuxilongwa okuhlukile kwesifo senhliziyo, i-atherosclerosis nezinye izifo.


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Isixazululo se-Clinical Chemistry

Uchungechunge

Igama Lomkhiqizo

Abbr

I-Lipid Metabolism

I-Apolipoprotein A1

Isiqephu A1

I-Apolipoprotein B

Apo B

I-Apolipoprotein E

Apo E

I-Lipoprotein A

I-LP(a)

I-Triglyceride

TG

I-Cholesterol Ephelele

TC

I-High Density Lipoprotein Cholesterol

I-HDL-C

I-Low Density Lipoprotein Cholesterol

I-LDL-C

I-Cholesterol encane eminyene I-Low Density Lipoprotein

sd LDL-C

I-Lipid metabolism ibhekisa ekwakhiweni kwamafutha amaningi emzimbeni ngokufakwa kwenyongo ibe yizinhlayiyana ezincane, i-pancreatic kanye ne-endocrine lipase hydrolysis yama-fatty acids abe ama-fatty acids mahhala kanye ne-glycerol monoesters.Ama-molecule amancane ane-hydrolyzed, njenge-glycerol, ama-acids ama-chain amafushane naphakathi, amuncwa amathumbu amancane emgudwini wegazi.Ngemva kokumuncwa kwama-monolipids namafutha eketango elide, ama-triglycerides aqala ukuhlanganiswa kabusha kumangqamuzana amancane amathumbu futhi akhe ama-phospholipids, i-cholesterol, namaprotheni abe ama-chylomicrons, adlula ohlelweni lwe-lymphatic angene egazini.

I-ApoA1 iyiphrotheni eyinhloko yesakhiwo ye-high-density lipoprotein (HDL), engasusa i-cholesterol kumaseli futhi ivimbele isifo sokuqina kwemithambo yegazi.Ngakho-ke, ukuzimisela kwe-ApoA1 kuhlanganiswe nokutholwa kwezinye izinto ze-lipid (i-cholesterol, i-triglyceride, i-apolipoprotein B, njll.) inenani elisizayo lokuxilonga lokuhlola isifo senhliziyo.

I-ApoB iyiphrotheni enkulu yesakhiwo ye-low-density lipoprotein (LDL), ehambisa i-cholesterol kumaseli futhi ngenxa yalokho ihlotshaniswa nokwakheka kwama-atherosclerotic plaque.Ngakho-ke, ukuzimisela kwe-ApoB kuhlangene nokutholwa kwezinye izinto ze-lipid (i-cholesterol, i-triglyceride, i-apolipoprotein B, njll.) kunenani elisizayo lokuhlola ukuze kuhlolwe ingozi yesifo senhliziyo kanye nokuphazamiseka kwe-lipoprotein metabolism.

I-Lp(a) i-dimer eyakhiwe ama-molecule e-LDL aboshwe ku-Apo(A), enomthelela we-atherogenic.I-Lp(a) iyingozi yesifo senhliziyo esizimele ngaphandle kwamanye amapharamitha we-lipid, futhi inenani eliphezulu lokuqagela ingozi yesifo senhliziyo, ikakhulukazi lapho ukugxila kwe-Lp(A) ne-LDL kunyuswa kanyekanye.Ngakho-ke, ukutholwa kwe-Lp(A) kuhlanganiswe nokutholwa kwezinye izinto ze-lipid kunenani eliphakeme kanye nokubaluleka kokuxilongwa okuyisizayo kanye nokuxilongwa okuhlukile kwesifo senhliziyo, i-atherosclerosis nezinye izifo.

I-Triglycerides ama-ester akhiwa amaqembu amathathu e-hydroxyl ku-glycerol kanye nama-acid amathathu amaketanga amade.Ingxenye yenziwe esibindini futhi ingxenye ngokudla okugayiwe.Ukunqunywa kwe-triglyceride kusetshenziselwa ukuxilongwa kanye nokuqapha ukusebenza ngempumelelo kwesifo sikashukela, i-nephropathy, ukuvinjwa kwesibindi, ukuphazamiseka kwe-lipid metabolism kanye nezifo ezahlukahlukene ze-endocrine.Kubaluleke kakhulu futhi kunenzuzo ekuxilongweni okuyisizayo kanye nokuxilongwa okuhlukile kwesifo senhliziyo kanye ne-lipoproteinemia yomndeni.

I-cholesterol synthesis itholakala yonke indawo emzimbeni futhi iyingxenye enkulu yolwelwesi lwamaseli nama-lipoprotein.Ukunqunywa kwe-cholesterol kubaluleke kakhulu futhi kunenzuzo ekuhlolweni kwengozi ye-atherosclerosis, ukuqapha ukuphazamiseka kwe-lipid metabolism, ukuqapha umphumela wokwelapha, ukuxilongwa okuyisizayo kanye nokuxilongwa okuhlukile kokungondleki, isifo sesibindi nezinye izifo ze-metabolic.

I-High-density lipoprotein (i-HDL) inesibopho sokuhlehla kwe-cholesterol isuka kumaseli ajikelezayo iye esibindini.Esibindini, i-cholesterol iguqulwa ibe yi-bile acid, ehamba nge-biliary tract iye emathunjini.Ucwaningo lwe-Epidemiological kanye nomtholampilo luye lwafakazela ukuthi i-HDL-C ihlobene kabi nesifo senhliziyo, ngakho-ke kubaluleke kakhulu ukuqapha ukugxiliswa kwe-serum HDL-C ngokomtholampilo.I-HDL-C ephakeme isiza ukuvikela isifo senhliziyo, kuyilapho ukugxilisa kwe-HDL-C ephansi, ikakhulukazi uma kuhlotshaniswa nokugxila kwe-triglyceride ephakeme, kwandisa ingozi yesifo senhliziyo nemithambo yegazi.I-cholesterol ihlanganiswa namaseli e-somatic futhi amuncwa ekudleni, ahanjiswe ngama-lipoprotein ku-serum.

I-low-density lipoprotein (LDL) ihilelekile ekuthutheni i-cholesterol kumaseli aseduze, futhi i-LDL-C idlala indima ebalulekile ekuthuthukisweni nasekuqhubekeleni phambili kwe-atherosclerosis kanye ne-coronary atherosulinosis.Ngakho-ke, ukutholwa kwe-LDL-C kuhlanganiswe nokutholwa kwezinye izinto ze-lipid kunenani eliphakeme kanye nokubaluleka kokuxilongwa okuyisizayo kanye nokuxilongwa okuhlukile kwesifo senhliziyo, i-atherosclerosis nezinye izifo.

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