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Ikhithi Yokuhlola Isifo sikashukela sohlobo I, i-C-luminary biotechnology

Type I Diabetes Test Kit, C-luminary biotechnology Featured Image
  • Type I Diabetes Test Kit, C-luminary biotechnology

incazelo emfushane:

Isifo sikashukela soHlobo I, esaziwa nangokuthi yi-insulin-dependent diabetes mellitus (IDDM) noma i-juvenile diabetes mellitus, sibangelwa ukungathuthuki kwamasosha omzimba noma ukucindezelwa kwamasosha omzimba, lapho isifo sikashukela i-ketoacidosis (DKA) sivame ukwenzeka khona.


  • Intengo ye-FOB:US $0.5 - 9,999 / Ucezu
  • Inani elincane le-oda:100 Isiqephu/Izingcezu
  • Ikhono Lokuhlinzeka:10000 Ucezu/Izingcezu Ngenyanga

    • Imininingwane Yomkhiqizo

    Omaka bomkhiqizo

    Isixazululo se-Chemiluminescent (i-Autoimmune Diseases)

    Uchungechunge

    Igama Lomkhiqizo

    Abbr

    UhloboⅠIsifo sikashukela

    I-Anti-Glutamic Acid Decarboxylase Antibody

    I-GAD

    I-Anti-Islet Cell Antibody

    I-ICA

    I-Anti-Tyrosine Phosphatase Antibody

    IA2

    I-Anti-insulin Antibody

    IAA

    I-Anti-Zinc Transporter 8 Antibody

    ZnT8

    I-Glutamate decarboxylase (GAD) itholakala ikakhulukazi kuma-neurons amaphakathi namaseli e-islet kuzilwane ezinomgogodla nakubantu.Ama-isoenzymes amabili (GAD85 kanye ne-GAD67) akhona, i-GAD67 ikhona kuphela kuma-islet B amaseli womuntu.I-Anti-Islet Cell Antibody (ICA) ukuphela kwe-antibody ethile engacekela phansi ngokuqondile izingxenye ze-β cell eziqhingini.I-Positive ICA ingabikezela umonakalo omkhulu we-β cell, ongasetshenziswa njengenye yezinkomba ezisengozini enkulu yohlobo loku-1 lwesifo sikashukela.

    I-Anti-Tyrosine Phosphatase Antibody (IA2), eyaziwa nangokuthi i-islet cell-associated protein-2.Ukutholwa okuhlanganisiwe kwe-anti-protein tyrosine phosphatase antibody kanye ne-anti-glutamate decarboxylase antibody kungathuthukisa ukuzwela kokuxilongwa kwe-autoimmune T1DM.Iziguli ze-T1DM ezine-anti-protein tyrosine-phosphatase antibody zinezimpawu zomtholampilo zeminyaka yangaphambili, isifo esifushane, ukusebenza kwe-islet okuphansi kanye nesidingo esikhulu se-insulin yangaphandle.

    Ukuhlushwa kwe-Anti-Insulin Autoantibody (IAA) kuhambisana ngokuphambene neminyaka yesiguli, futhi kuphezulu ezigulini ezingaphansi kweminyaka engu-5 ubudala.Kucatshangelwa ukuthi lapho ama-T cell elamula ukucekelwa phansi kwamaseli B, ukuhlangana kwezinhlangothi ezintathu kwe-insulin ye-endogenous kuyashintsha, okuholela ku-antigenicity kanye nokuvusa ukusabela kwe-antibody.I-IAA ivela ohlotsheni loku-1 lwesifo sikashukela kanye neziguli ezandulela umtholampilo, kanti izinga elihle le-IAA lingama-40-50% ezigulini ezixilongwayo zesifo sikashukela sohlobo 1, kanti i-IAA ingatholwa ezigulini ezingabantu abadala ezinesifo sikashukela esizimele.I-IAA enhle ingase yenzeke ku-insulin autoimmune syndrome kanye nesifo se-thyroid, kanti abanye abantu abavamile nabo banethemba.Ngakho-ke, i-IAA enhle ayinakho ukucaciswa kokutholwa kwesifo se-islet, kodwa ingabonisa ukuthambekela kwe-autoimmune ukuthuthukisa isifo se-islet.

    I-ZnT8A iyi-antibody ethile esanda kutholwa yokuxilongwa kwesifo sikashukela sohlobo loku-1, izinga layo elihle liseduze nele-anti-GAD antibody ezimeni zokuqala zesifo sikashukela sohlobo loku-1.Ukutholwa kwe-ZnT8A kuzosiza ukuhlola ubungozi besifo sikashukela sohlobo loku-1 futhi kunenani eliphakeme lokuxilonga kanye nelokubikezela kwezihlobo zezinga lokuqala zeziguli ezinesifo sikashukela.

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